| 1938 |
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Albert Hofmann, a chemist working for Sandoz Pharmaceutical, synthesizes LSD-25 for the first time in Basel, Switzerland while looking for a blood stimulant. LSD research is not continued until 5 yrs later. |
| Apr 16, 1943 |
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Albert Hofmann accidentally experiences a small amount of LSD for the first time. This is the first human experience with pure LSD-25. He reports seeing "an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopelike play of colors." The experience lasted just over two hours. |
| Apr 19, 1943 |
|
Bicycle Day - Albert Hofmann intentionally takes (250 ug) LSD for the first time. This is the first intentional us of LSD. 1 |
| 1947 |
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First article on LSD's mental effects published by Werner Stoll in the Swiss Archives of Neurology. |
| 1949 |
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Dr. Max Rinkel brings LSD to the United States from Sandoz Pharmaceuticals in Switzerland and initiates work with
LSD in Boston; Nick Bercel commences LSD study in Los Angeles. 2 |
| 1950 - 1960 |
|
Hundreds of papers published discussing LSD. |
| May 1950 |
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First article about LSD appears in the American Psychiatric Journal. 2 |
| 1951 |
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CIA becomes aware of and begins experimenting with LSD. |
| 1951 |
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Al Hubbard first tries LSD. 2 |
| 1952 |
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Charles Savage publishes the first study on the use of LSD to treat depression. |
| 1953 |
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First LSD clinic opened to the public in England under Ronald Sandison. Separately, unwitting subjects in the United States were given LSD in the CIA funded Project MK-Ultra to test the effects of the drug. |
| 1953 |
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Dr. Humphrey Osmond begins treating alcoholics with LSD. 2 |
| 1955 |
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First conferences focusing on LSD and mescaline take place in Atlantic City and Princeton, N.J. |
| 1955 |
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Aldous Huxley first takes LSD. The publication of Huxley's 'Heaven and Hell'.
2 |
| 1959 |
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Josiah Macy Foundation sponsors major scientific congress on LSD. 2 |
| 1959 |
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Allen Ginsberg tries LSD for the first time. 2 |
| 1960 |
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Harvard University's Timothy Leary establishes the Psychedelic Research Project. |
| 1962 |
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Congress passes new drug safety regulations and the FDA designates LSD an experimental drug and restricts
research. The first LSD related arrests are made by the FDA. 2 |
| 1963 |
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LSD first appears on the streets (liquid on sugar cubes). Articles about LSD first appear in mainstream media (Look, Saturday Evening Post). 2 |
| May 1963 |
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Timothy Leary and Richard Alpert are fired from Harvard. 2 |
| Feb 1965 |
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Owsley "Bear" Stanley first succeeded in synthesizing crystalline LSD. Earliest distribution was March 1965. 3 |
| 1966 |
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Leary founds the League of Spiritual Development, with LSD as the sacrement. 4 |
| Mar 25, 1966 |
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Life publishes cover article on LSD. "LSD: The Exploding Threat of the Mind Drug that Got Out of Control". |
| Apr 1966 |
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Sandoz Pharmaceutical recalled the LSD it had previously distributed and withdrew its sponsorship for work with LSD. 4 |
| Oct 6, 1966 |
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LSD becomes illegal in California. 5 |
| 1967 |
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Summer of Love in San Francisco. First human be-in. |
| 1967 |
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LSD banned federally in the U.S. |
| Summer 1969 |
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Orange sunshine acid first appears. 2 |
| 1970 |
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An estimated 1-2 million Americans have used LSD. |
| Oct 27, 1970 |
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The Comprehensive Drug Abuse Prevention and Control Act is passed. Part II of this is the Controlled Substance Act (CSA) which defines a scheduling system for drugs. It places most of the known hallucinogens (LSD, psilocybin, psilocin, mescaline, peyote, cannabis, & MDA) in Schedule I. It places coca, cocaine and injectable methamphetamine in Schedule II. Other amphetamines and stimulants, including non-injectable methamphetamine are placed in Schedule III. |
| 1971 |
|
Windowpane acid first appears. 2 |
| Early 1970s |
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LSD impregnated paper ("blotter") first hit the streets. Very quickly the paper began being printed with colorful art. |
| mid 1970's |
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Blotter paper begins to emerge as the most common form of LSD sold on the street. Previously it had been tablets and powder, but blotter and gel-tabs proved more consistent in purity and potency. 6 |
| 1979 |
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Albert Hofmann publishes "LSD: My Problem Child." 1 |